Custom DNA
Manufacturing
Services for plasmids and Minicircles
At PlasmidFactory, we provide custom DNA manufacturing services for clients in life sciences, biotechnology, gene therapy, and pharmaceutical research. Our advanced platform delivers high-quality, custom plasmid DNA and Minicircle DNA, tailored to your exact specifications – whether for research, preclinical studies, or clinical applications.
Unlike standard DNA services, we use a biotechnological DNA production process based on E. coli replication, ensuring high sequence fidelity, minimal impurities, and a scalable workflow. Our DNA is not synthesized chemically but amplified biologically – producing highly pure, supercoiled DNA free from synthetic enzyme residues.
Whether you need expression vectors, therapeutic constructs, or gene editing components, PlasmidFactory delivers precision-engineered DNA constructs from Research to GMP Grade, optimized for your application.
Chose your product
Advanced quality control
All custom DNA undergoes stringent in-house quality controls, with the option to include additional, project-specific tests, including:
- DNA purity
- DNA topology: supercoiled vs open circular
- Endotoxin levels
- DNA yield and concentration
- NGS sequencing
- Host cell protein (via ELISA)
- Residual chromosomal DNA (via qPCR)
- RNA contamination analysis
- Many more
All tests are documented in a batch-specific report.
Our quality grades
Scalable plasmid and Minicircle DNA — from research to clinical manufacturing.
PlasmidFactory offers clearly defined quality grades to support every stage of your project — ensuring regulatory alignment, performance consistency, and seamless scale-up within one trusted CDMO.